In biological systems, life process is led by the unique behavior of macromolecules such as proteins and DNA. Molecular recognition by macromolecules plays an important role, for example, in substrate specificity of enzymes and antigen-antibody reactions in human life. Selective molecular recognition among macromolecules is achieved through a large number of weak interactions. We have focused our attention on the special behavior of antibodies, especially monoclonal antibodies, because they can recognize a larger and more complicated compound with high specificity than that can synthetic host molecules or enzymes.
In this laboratory, we develop novel materials through hybridization of bio-related macromolecules such as monoclonal antibodies with artificial/synthetic small molecules. We construct functionalized catalytic and energy conversion systems based on specific molecular recognition of biomacromolecules and selective assembly of bio/synthetic molecules.

MoreNews & Topics

7th Octorber, 2020
Our paper on "Supramolecular complex formation of polysulfide polymers and cyclodextrins" was published in Chem. Commun. (Publications updated.)
6th Octorber, 2020
Publications updated.
28th September, 2020
Collaborative research paper on "Control of microenvironment around enzymes by hydrogels" was published in Chem. Commun. (Publications updated.)
12th May, 2020
Our paper on "Ligand Exchange Strategy for Delivery of Ruthenium Complex Unit to Biomolecules Based on Ruthenium?olefin Specific Interactions" was published in Chem. Lett. (Publications updated.)
1th April, 2020
New members joined our laboratory. (Members)
1th April, 2020
Our paper on "A palladium-catalyst stabilized in the chiral environment of a monoclonal antibody in water" was published in Chem. Commun. (Publications updated.)
19th March, 2020
Farewell party for graduate

Congrats graduates!
We wish you luck in all your future endeavors.

19th March, 2020
Dr. Kobayashi recieved Award for Encouragement of Research in Polymer Science; The Society of Polymer Science, Japan (2019).
4th December, 2019
Dr. Takuma Adachi's work was highlighted on Chem-Station
Atroposelective antibodies as a designed protein scaffold for artificial metalloenzymes

This work was introduced on this site.